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RANITIDINE HYDROCHLORIDE

    Product Name: RANITIDINE HYDROCHLORIDE

    CAS NO.: 66357-35-5

    MF: C13H23ClN4O3S


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Specification:

Item

Specification

Appearance

White to pale yellow, crystalline, practically, odorless powder

Related substance (HPLC)

Total impurity ≤0.5%
     Max single impurity ≤0.1%

Odor

Characteristic

Assay

99%

Sieve analysis

100% pass 80 mesh

Loss on Drying
     Residue on Ignition

≤1.0%
     ≤1.0%

Heavy Metal

undefined10ppm

As

undefined0.1ppm

Pb

undefined0.1ppm

Cd

undefined0.1ppm

Residual Solvents

undefined100ppm

Residual Pesticide

Negative

Microbiology


Total Plate Count

undefined1000cfu/g

Yeast & Mold

undefined100cfu/g

E.Coli

Negative

Salmonella

Negative


Application:

Recurrent oral ulcer

Use of ranitidine in the treatment of recurrent aphthous ulcer, pain within 1-2 days 3-5 days to heal, the total effective rate of 100%, and metronidazole in the treatment of control group is 85%, there are significant differences. Usage: oral ranitidine 150 mg per time, 2 times per day, or ranitidine Ding Yan into fine powder and apply directly on the ulcer surface, 3 times per day until the symptoms disappear.


Mumps

Application of ranitidine in treatment of patients with mumps, the effect is significant, significantly better than the control group treated with Morpholine croak. Usage: oral ranitidine, 15 mg/kg ·, 2 suits, for 3 days in a row. If the heat is too high, and with physical cooling.


Ulcerative colitis

Ranitidine was used to treat patients with ulcerative colitis, the total effective rate of 95%. Usage: oral ranitidine 150 mg per time, daily morning and evening 1, taken in March.


Verrucous gastritis

Application of ranitidine in the treatment of Verrucous gastritis and achieve significant efficacy in one week, the total effective rate of 87%, while the control group only 33%, very significant differences between the two groups. Usage: oral ranitidine 150 mg per time, morning and evening, 1 times, warm water delivery service, for 1 course of 5 weeks.


Eosinophilic Fasciitis

Application of ranitidine in treatment patients with Eosinophilic Fasciitis, with good results. General Medicine 1 month can be effective six months after the partial recovery of skin lesions. Usage: oral ranitidine 150 mg per time, early, middle and late each take 1 times, warm water delivery service.


Non-ulcer dyspepsia

Oral administration of ranitidine hydrochloride for the treatment of patients with non-ulcer dyspepsia, the effect is significant, remission rate of 76%, the treatment group than the control group. Usage: oral ranitidine 150 mg per time, 2 times per day for 6 weeks.


Chronic diarrhea

The disease may lead to increased intestinal mast cells, have been stimulated to release histamine, causing local congestion, edema, muscle cramps and diarrhea occurs. Ranitidine works by inhibiting histamine release and to good effect. Most patients stool within 1 week, less often, and get the healing effect. Usage: oral ranitidine 150 mg per time, early, middle, late 1 times, warm water delivery service.


Herpes Simplex

Use of ranitidine in the treatment of Herpes Simplex, typically coated with 3~5 pain away, early cases without a blister, blister blister dries up, scabs in 2 days. Ranitidine was also used in the treatment of 29 cases of herpes simplex are cured within 2-4 days. And no scar after healing occurs. Usage: take ranitidine capsules (150 mg), 1 capsule, the powder dissolved in water, made of exterior coating solution on the affected area, dressing 1 1-2 hours.


Urticaria

Application of ranitidine in the treatment of urticaria, is satisfactory with medication after 1 treatment efficiency of 80%, the total effective rate of 90%. Methods: 5% ranitidine Ding Shuang agent, application of Yu Shenjue, wind pool, Xuehai, each point 50 mg, covers 3.5~6 square tape wound 1 time every 3 days, 2 times for 1 course, continuous treatment until symptoms disappear.


Von Willebrand disease

Application of ranitidine in the treatment of hemophilia, can increase plasma levels of factor VIII or factor IX, clinical symptoms improved, after 12 hours to stop bleeding. Usage: oral ranitidine 150 mg per time, morning and evening, 1. Pediatric dosage by age descending, for 15 days. Another continuous maintenance treatment with ranitidine, were also better efficiency.


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